Molecular Genetics Webtext
- An online textbook on chromosomes, principles of genetic engineering, basic molecular genetics and experimental methods.
- http://opbs.okstate.edu/~melcher/MG/FMG01.html
Reportergene - Information and news related to reporter genes, that are used to monitor activation of genes and groups of genes that are otherwise difficult to follow. - http://reportergene.blogspot.com/
Epigenetics Research - News, jobs, recent literature, lab registry and an ontologically driven database that is updated daily. - http://www.epidna.com
RiboWeb Project - Knowledge base that combines data on the structure of the prokaryotic 30S ribosomal subunit that initiates the translation of mRNA into protein, its function and related links and references. - http://helix-web.stanford.edu/ribo3dmodels/index.html
Control of Gene Expression - A collection of diagrams illustrating the fundamentals of molecular biology. - http://www.accessexcellence.org/RC/VL/GG/ecb/gene_expression.html
Laboratory of Intelligent Systems - Project at the Ecole Polytechnique Fédérale de Lausanne (EPFL) creating electronic models of the evolution of gene expression, neural development and similar evolution processes. - http://lis.epfl.ch
Epigenetic Station - With information, protocols and resources about epigenetics and DNA methylation and much advertising. - http://www.epigeneticstation.com
Epigenetics - Article on the site of CellCentric on epigenetics. - http://www.cellcentric.co.uk/epigenetics.htm
The Epigenome Network of Excellence - Network of research groups on heritable changes in gene expression without a change in DNA sequence, funded by the European Union. - http://www.epigenome-noe.net/
European Sequencing of Tobacco - A collaboration between Advanced Technologies (Cambridge) Ltd and Tobacco Institute of Bergerac to sequence a large number of tobacco genes. - http://www.estobacco.info
Epigenetic inheritance - Transmission of information from a cell or multicellular organism to its descendants without that information being encoded in the nucleotide sequence of the gene. Wikipedia article. - http://en.wikipedia.org/wiki/Epigenetic_inheritance
Gene Expression - Independent forum for discussion of gene expression. - http://www.gnxp.com
Transfer RNA - Wikipedia article: small RNA molecules that transport amino acids to their positions on the ribosome during polypeptide synthesis. - http://en.wikipedia.org/wiki/Transfer_RNA
Transcription Factor - Proteins that specifically bind to promotor or enhancer regions on DNA and thereby control the transcription of the downstream gene. - http://en.wikipedia.org/wiki/Transcription_factor
Translation - Wikipedia article: in genetics, the process by which ribosomes in the cytoplasm transfer the genetic code from a m-RNA sequence to an amino acid sequence in a polypeptide chain. - http://en.wikipedia.org/wiki/Translation_%28genetics%29
Transcription - Wikipedia article: in genetics the process by which a DNA sequence is converted to a corresponding RNA sequence. - http://en.wikipedia.org/wiki/Transcription_%28genetics%29
Splicing - Wikipedia article: in genetics, the process of removing introns from mRNA in the cell nucleus before export to the cytoplasm and use as master for protein synthesis. - http://en.wikipedia.org/wiki/Splicing_%28genetics%29
Spliceosome - Wikipedia article: particle composed of DNA and peptide chains that effects mRNA splicing in the cell nucleus of eucaryotic cells. - http://en.wikipedia.org/wiki/Spliceosome
Signal peptide - Wikipedia article: short peptide sequences that direct the post-translational transport of proteins after synthesis. - http://en.wikipedia.org/wiki/Signal_peptide
Shine-Dalgarno sequence - Wikipedia article: signals the initiation of protein synthesis in bacteria. - http://en.wikipedia.org/wiki/Shine-Dalgarno_sequence
SECIS element - Wikipedia article: Sequence that directs translation of UGA as selenocysteine insteado of using it as a stop codon. - http://en.wikipedia.org/wiki/SECIS_element
Protein biosynthesis - Wikipedia article: summary of the process by which the cell converts the DNA sequence proteins. - http://en.wikipedia.org/wiki/Protein_biosynthesis
Promoter - Wikipedia article: in genetics a sequence located upstream of a gene that enables its translation. - http://en.wikipedia.org/wiki/Promoter
Pre-mRNA - Wikipedia article: RNA string syntesized in the cell nucleus before modification (splicing, polyadenylation) and export to the cytoplasm. - http://en.wikipedia.org/wiki/Pre-mRNA
Posttranslational modification - Wikipedia article: chemical modification of polypeptide chains after synthesis. - http://en.wikipedia.org/wiki/Posttranslational_modification
Operon - Wikipedia article: group of genes in primitive organisms that are controlled by one operator and one promoter to be activated together. - http://en.wikipedia.org/wiki/Operon
Noncoding DNA - Wikipedia article: sections of DNA that do not contain codes for polypeptide sequences. - http://en.wikipedia.org/wiki/Noncoding_DNA
Monocistronic - Wikipedia article: Messenger RNA that codes for one polypeptide string only. - http://en.wikipedia.org/wiki/Monocistronic
Messenger RNA - Wikipedia article on the RNA that carries information from DNA to protein synthesis. - http://en.wikipedia.org/wiki/Messenger_RNA
Imprinting - Wikipedia article on the suppressing of genes by chemical modification, depending on which parent they were received from. - http://en.wikipedia.org/wiki/Imprinting_%28genetics%29
Genetic Code - Wikipedia article on the relationship between the nucleic acid base sequence and the corresponding polypeptide amino acid sequence. - http://en.wikipedia.org/wiki/Genetic_code
Gene Regulatory Network - Wikipedia article on the mathematical modelling of gene expression as a network. - http://en.wikipedia.org/wiki/Gene_regulatory_network
Gene Regulation - Wikipedia article on the mechanisms that regulate gene expression. - http://en.wikipedia.org/wiki/Gene_regulation
Expressed Sequence Tag - Wikipedia article: EST are short sub-sequences of genes, used in mRNA sequencing and in construction of DNA microarrays. - http://en.wikipedia.org/wiki/Expressed_sequence_tag
Intron - Wikipedia article on sections of genes that are eliminated by splicing in the formation of mature mRNA and therefore not expressed as proteins. - http://en.wikipedia.org/wiki/Intron
Exon - Wikipedia article on regions in genes that are expressed in mature mRNA and in proteins. - http://en.wikipedia.org/wiki/Exon
Enhancer - Wikipedia article on enhancers, short pieces of DNA which bind to trans-acting factors to enhance transcription levels of genes. - http://en.wikipedia.org/wiki/Enhancer
Alternative Splicing - Wikipedia article on the process in eukaryotes in which the splicing process of a pre-mRNA can lead to different ripe mRNA molecules and therefore to different proteins. - http://en.wikipedia.org/wiki/Alternative_splicing
3'UTR - Wikipedia article on the untranslated regions at the ends of mRNA. - http://en.wikipedia.org/wiki/3%27_UTR
Serial Analysis of Gene Expression - Explanation of Serial Analysis of Gene Expression (SAGE), a method for analysis of gene expression patterns. - http://www.sagenet.org/
Anatomy of a Comparative Gene Expression Study - Clear explanation of the process of comparing the gene expression in two cell populations or tissue samples by fluorescent microarray technique. - http://www.cs.wustl.edu/~jbuhler/research/array/
Genome-Wide Expression - Report on a project to analyze the transcriptional regulatory circuitry of the yeast cell. From the Young Lab at the Whitehead Institute for Biomedical Research. - http://web.wi.mit.edu/young/expression/home.html
Gene Expression: Transcription - Resource for transcription events during gene formation including schematic diagrams. - http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Transcription.html
Biochemistry of Nucleic Acids - Lecture notes on nucleic acid structure, DNA replication and repair, the genetic code and translation, as well as cancer genes, from Oregon State University, USA 2003. - http://oregonstate.edu/instruction/bb492/general/schedule.html
Mammary Genome Anatomy Project - Forum to integrate various aspects of mammary gland biology, including cellular and developmental aspects, and to promote collaborations and the exchange of ideas, knowledge and resources at NIH, Maryland. - http://mammary.nih.gov/
Genomes to Life - The US Department of Energy at Oak Ridge program for research in moleular biology: goals and results. - http://doegenomestolife.org/
Role of the Ribosome - Illustrated explanation of the ribosomal protein synthesis by Gwen V. Childs, University of Texas, Galveston, TX. - http://cellbio.utmb.edu/cellbio/ribosome.htm
Ribosomes - Explanation of how the information encoded in mRNA is translated into a polypeptide. Includes differences between prokaryotes and eukaryotes by John W. Kimball, now retired from Harvard College. - http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/R/Ribosomes.html
Eukaryotic Gene Expression Problem Set - Multiple choice questions about post-transcriptional modification of RNA, promoters, and nuclear RNA processing. From: University of Arizona, USA 1997. - http://www.biology.arizona.edu/molecular_bio/problem_sets/mol_genetics_of_eukaryotes/eukaryotes.html
Regulation of Gene Expression - Overview of different aspects of gene expression, including transcription, chromatin modification, and analysis of whole genomes, from Massachusetts Institute of Technology, Cambridge, Mass, USA. - http://web.wi.mit.edu/young/pub/regulation.html