Siskiyou Development
- Offers service stations, a motel and RV Park with accompanying restaurant and catering. Service station locations in Yreka, Weed and Mt. Shasta.
- http://www.sisdevco.com

Volf Construction
- Building custom home in Siskiyou County for over 22 years.
- http://www.snowcrest.net/volfcon/

Siskiyou County Oil Changer
- 10 Minute oil change serving Siskiyou County and travelers on Interstate 5.
- http://www.10-minute-oil-changer.net/

Weldon's Tire Services
- Tires and tire services serving all of Siskiyou County.
- http://www.siskiyou-county-tires.com

Alpine Veterinary
- Mobile veterinarian serving Yreka, Mt. Shasta, Weed, Fort Jones, Dunsmuir and all of Siskiyou County. Dogs, cats, horses, birds, reptiles and more are helped at your home.
- http://www.siskiyou-county-vet.com/

Workforce Connection
- Community employment center with locations in Yreka and Weed.
- http://www.siskiyouwc.org/

Siskiyou County Economic Development Council
- Provides a wide range information about economic development programs and services for Siskiyou County, together with detailed Census demographic data and helpful links.
- http://www.siskiyoucounty.org/

Siskiyou Communications, Inc.
- Cellular telephone, cable television and Internet provider.
- http://www.sisqtel.net/