Mizzou Linux Users Group (MLUG)
- With over 400 members, an invaluable resource for Linux and open source computing across the Midwest. Mailing list, meetings, and resources.
- http://mlug.missouri.edu/

ArchLUG, St. Louis
- A Linux and Open Source Users group for the St. Louis region's individuals, businesses, and community. The website contains a wiki, meetings information, a calendar and a web forum.
- http://www.archlug.org/

Truman State Linux Users Group
- The Linux User Group at Truman State University in Kirksville, Missouri.
- http://tslug.truman.edu/

St.Louis Linux User's Group
- The St. Louis Linux Users Group holds meetings on the third Thursday of every month. Meetings are free and open to everyone.
- http://www.stllinux.org/