Bersirc - Fully featured Windows IRC client with an attractive interface and powerful scripting capabilities. - http://bersirc.free2code.net/index.php/home
IRCmmm - IRC Client written in C# .NET. Similar look to MSN messenger. - http://sourceforge.net/projects/ircmmm/
leafChat - Advanced IRC client for Windows with many useful functions and features. - http://www.leafdigital.com/software/leafchat/
TalkSoup - A GNUstep IRC client built on the extensibility of the Objective-C language. The entire client is implemented by plugins, so one can pick and choose what they want to use. - http://talksoup.aeruder.net/
KvIRC - Unix based IRC client. Contains screenshots, client news, help and support, features list and miscellaneous section. - http://www.kvirc.net
Vortec IRC - Includes client news, support, screenshots, and contact information. - http://www.vortecirc.com
CGI:IRC - A Web based IRC Client written in Perl with a simple but powerful interface. - http://cgiirc.sourceforge.net/
Ghoti - Feature-rich, GUI based IRC client for unix, written in perl-tk. - http://ghoti.linuxbox.co.uk
ircII EPIC4 for OpenVMS - A port of the ircII EPIC4 Unix IRC client to the OpenVMS operating system. - http://www.2mbit.com/~larne
HydraIRC - Fast, feature packed and customizable, handles multiple-servers. Open Source, written in C++/WTL. - http://www.hydrairc.com/
ERC - An Emacs IRC client. - http://www.emacswiki.org/cgi-bin/wiki.pl?EmacsIRCClient
WavGet - Easy to use freeware and shareware. Home of Wavget, Sweep, ICE, and Adwizard. - http://www.wavget.com/
IRCJunkie - Website for IRC users. News, articles, quotes and funny logfiles. - http://www.irc-junkie.org/
SpiffyStats - Windows-based IRC statistics generator. Generates detailed stats based on your channel's log files. - http://fundamentallogic.ath.cx
Real 3D Chat - Allows you to chat in real 3D in front of functional, scrollable Webpages with avatars who talk via bubbles. - http://www.spatialknowledge.com/projects/clara/
dIRC - Windows IRC client. Support connections to multiple connections, numerous scripting languages, and other unique features. - http://www.dircchat.com/
SharpIRC - A GPL'd IRC client written in C#. - http://sharpirc.sourceforge.net/
EPIC - Popular ircII-based IRC client with added features. - http://www.epicsol.org/
IRCXpro - IRC client that works exactly like an instant messenger. - http://www.ircxpro.com/
upIRC - An IRC client for PalmOS. - http://www.smittyware.com/palm/upirc/
IceChat - Simple, Multi Server IRC Client with a unique interface. - http://www.icechat.net
TurboIRC - Windows IRC client with enhanced features and scripting capabilities. - http://www.turboirc.com/
BitchX - The most popular IRC client for UNIX. Based on ircII. - http://www.bitchx.org/
IRCfs - Standalone IRC file server for Linux. - http://ircfs.sourceforge.net/
XChat - A GTK+ X-windows client with Perl and Python scripting support. - http://www.xchat.org/
savIRC - An IRC Client written in the tcl/tk programming language. Both Windows and Linux compatible. Contains screenshots, news, Forum, download area and documentation. - http://www.savirc.com/
Klient - Windows IRC client. Uses DLLs rather than scripting to increase speed and lower processor demand. - http://www.klient.com/
.IRC - Full Featured Windows .NET IRC Client with built-in SSL (crypted) IRC support. - http://www.joher.com/dotIRC/
ircII project - The original IRC client. Contains downloads, information, and mailing lists. - http://www.eterna.com.au/ircii/
Irssi - Powerful text-based IRC client for UNIX with perl scripting support. - http://irssi.org