#2600
- The original IRC channel for the 2600 magazine.
- http://www.2600.com/

#SEO
- Search Engine Optimization discussion IRC channel.
- http://www.seohelp.org/

#IRChelp
- Provides help documents sorted by topic.
- http://www.irchelp.org/

#mIRCHelp
- Provides support for the popular IRC client mIRC.
- http://www.mirchelp.us/

#GayPortland
- Portland Oregon GLBT channel.
- http://www.gayportland.info/

#Winprog
- Provides support to programmers coding for the x86 platform.
- http://winprog.org/

#mIRC
- Provides free support for the popular IRC client mIRC.
- http://mirc.stealth.net/

#webchat
- Providing web to IRC services on EFnet.
- http://chat.efnet.org/

#mIRC4Dummies
- Provides help for mIRC newbies.
- http://mirc4dummies.ice-cold.net/

#politics
- Vent your political views in this evenly moderated channel.
- http://www.ircpolitics.org/

#math
- Discussions about all things related to mathematics and statistics.
- http://www.efnet-math.org/

#Israel
- Community for folks from the country Israel.
- http://www.channel.israel.net/

#help
- Contains tips, advices, and stats for the channel #help
- http://www.networks.org/?feed=chat-irc-help