Spork Rivers
- Fantasy-themed comic about a dull town that becomes over-run with unusual creatures. Updated Sundays and Wednesdays.
- http://sporkrivers.comicgenesis.com/

Swirly Mark Yume
- Fantasy comic about how a prophet predicts the end, but only his son believes, and goes on a quest to save the world.
- http://swirlymark.comicgenesis.com/

Swift Dagger - Online Comic
- Original, online comic with manga based style that centers around angelic, demonic, and medieval topics. Yaoi warning.
- http://swiftdagger.comicgenesis.com/

Stoic
- A teenager's struggle with life reveal to him what it means to be truly human.
- http://stoic.comicgenesis.com/

Squadron 509
- A destructive manga with bombs, addiction, and other strange quirks centering around an oddball cast.
- http://squadron509.comicgenesis.com/

Shifters: The Beast Within
- Follows the adventures of a group of teenaged werebeasts as they become embroiled in the secret world of the Veil. Updated three times weekly.
- http://shifters.comicgen.com/

Schizophrenics
- When fan-created characters get out of hand. Features creations inspired by Dragonball and Star Wars.
- http://schizophrenics.comicgenesis.com/

Saturnalia
- In the year 2999, an arrogant young cop struggles to keep his job amid a muddled relationship with his ex and a secret life that goes against all the principles of his job.
- http://saturnalia.comicgenesis.com/

Strange Fruit
- An online yaoi manga about dealing with life and the impending Apocolypse. Updated weekly.
- http://www.astrangefruit.net/

Shonen Punk!
- Perverted comedy. A girl pops out of a raunchy DVD and become Chitsu's wife.
- http://www.shonenpunk.com

A Star Cross'd Destiny
- Furturistic fantasy. A group of outcasts fight to survive in a world that shuns them as freaks.
- http://starcrossd.net

Shunkoku Kaosu - Instachaos
- Four friends have accidentally destroyed their favorite hangout, an old pool place by the highway. Now they have to find a new place to loiter around.
- http://www.shunkoku-kaosu.com

Skyscraper Soup
- The Rift, a science fiction and fantasy comic. Also features original artwork.
- http://skyscrapersoup.com/

Spikecomix
- Hosts Jagged Blade, an Amerimanga about intertwined fates in a post apocalyptic cityscape. Also hosts love^3, Squirrel, and Back Issues.
- http://spikecomix.canadaka.net/

SkyFall
- An original fantasy webmanga/comic by RekKa and Mirai filled with action, comedy, bishounen, a hint of romance (of the shounen-ai flavor).
- http://www.skyfallmanga.com

Sparkling Generation Valkyrie Yuuki
- Comedy in which a young male magical-girl enthusiast is suddenly transformed into the magical, female title character.
- http://www.montroseacademy.com/

Shonen Chikara
- A parody manga about four guys summoned by a loud, annoying, smelly old man to fight against girl power. In skirts.
- http://www.shonen-chikara.com/

The Showcase
- Short comics, images, and links.
- http://www.showcasecomics.co.uk/